Publications

X. Tan, A.P. Liu, Clathrin-mediated endocytosis regulates fMLP-mediated neutrophil polarization, to be submitted.

N. Emery, A.P. Liu, Synergistic nucleic acid production by T7 RNA polymerase and Bsu DNA polymerase in the absence of canonical substrates, to be submitted.

S. Wang, S. Majumder, N. Emery, A.P. Liu, Realtime monitoring of transcription and translation in mammalian cell-free expression in bulk and in cell-sized droplets, to be submitted.

S. Majumder, A.P. Liu, Bottom-up synthetic biology: modular design for making artificial platelets, submitted.

F. Ma*, M.T. Chung*, Y. Yao, R. Nidetz, L.M. Lee, A.P. Liu, Y. Feng, K. Kurabayashi, G-Y Yang, Efficient molecular evolution for generating enantioselective enzymes by a dual-channel microfluidic droplet screening platform, submitted.

L.K. Rosselli-Murai, M.G.G. Contessotto, M.C. Garcia, C.L.P. Oliveira, I.L. Torriani, I. Lopes-Cendes, A.P. Liu, M.J. Murai, Expansion of polyglutamine tract in deubiquitinase ataxin-3 alters its molecular envelope and impacts dynamics of clathrin-coated pits, submitted.

2017

M. DeNies, L.K. Rosselli-Murai, V.L. Murray, E.M. Steel, A.P. Liu, Proximity biotinylation for studying G protein-coupled receptor dimerization (book chapter), Neuromethods, accepted.

X.-S. Wu, S. Elias, H. Liu, J.Heureaux, P.J. Wen, A.P. Liu, M.M. Kozlov, L.-G. Wu, Membrane tension inhibits rapid and slow endocytosis in secretory cells, Biophysical Journal, accepted.

A.P. Liu*, R.J. Botelho*, C.N. Antonescu*, The big and intricate dreams of little organelles: embracing complexity in the study of membrane traffic, Traffic, 18 (9): 567-579, 2017.  [article link] * equal contribution; Botelho and Antonescu are co-corresponding authors. 

L.K. Rosselli-Murai, J.A. Yates, S. Yoshida, J. Bourg, K.K.Y. Ho, M. White, J. Prisby, X. Tan, M. Altemus, L. Bao, Z.-F. Wu, S.L. Veatch, J. Swanson, S.D. Merajver*, A. P. Liu*, Loss of PTEN promotes formation of signaling-specific clathrin-coated pits, bioRxiv, 137760; doi: https//doi.org/10.1101/137760, 2017. [article link] * corresponding author

S. Majumder*, J. Garamella*, Y.-L. Wang, M. DeNies, V. Noireaux, A.P. Liu, Cell-sized mechanosensitive and biosensing compartment programmed by DNA, ChemComm, 52, 7349-7352, 2017. [article link] * equal contribution; A.P. Liu and V. Noireaux are co-corresponding authors.

Y. Zheng*, S. Wang*, X. Xue, A. Xu, W. Liao, A. Deng, G. Dai, A.P. Liu, J. Fu, Dll4-Notch signaling in regulating angiogenesis in a 3D biomimetic environment, Lab on a Chip, 17. 1948-1959, 2017. [article link] * equal contribution; A.P. Liu and J. Fu are co-corresponding authors.

A.P. Liu*, O. Chaudhuri*, S. Parekh*, New advances in probing cell-extracellular matrix interactions, Integrative Biology, 9, 383-405, 2017. [article link]   * equal contribution and corresponding author (top 10 downloaded article published in Integrative Biology in 2017)

K.K.Y. Ho, J.W. Lee, G. Durand, S. Majumder, A.P. Liu, Protein aggregation with poly(vinyl) alcohol surfactant reduces double emulsion-encpasulated mammalian cell-free expression, PLoS One, 12(3): e0174689, 2017. [article link] 

E. Irajizad, N. Walani, S.L. Veatch, A.P. Liu, A. Agrawal, Clathrin polymerization exhibits high mechano-geometry sensitivity, Soft Matter, 13, 1455-1462, 2017. [article link] 

2016

Q. Zhu, F. Zheng, A.P. Liu, J. Qian, C. Fu, Y. Lin, Shape transformation of the nuclear envelope during closed mitosis, Biophysical Journal, 111, 2309-2316, 2016. [article link] 

L.M. Lee*, J.W. Lee*, D. Chase, D. Gebrezgiabhier, A.P. Liu, Development of an advanced microfluidic micropipette aspiration device for single cell mechanics studies, Biomicrofluidics, 10, 054105, 2016. [article link] 

K.K.Y. Ho, L.M. Lee, A.P. Liu, Mechanically activated artificial cell by using microfluidics, Scientific Reports, 6, 32912, 2016. [article link] 

Z. Peng, O. Pak, A.P. Liu, Y.-N. Young, On the gating of mechanosensitive channels by fluid shear stress, Acta Mechanica Sinica, 32 (6), 1012-1022, 2016.  [article link]

P.J. Wen*, S. Grenklo*, E. Hamid, X. Tan, H.S. Liao, J. Heureaux, H.C. Chiang, W. Shin, W.D. Zhao, N. Toilin, E. Evergreen, L. Brodin, R. Karlsson, A. Jin, A.P. Liu, O. Shupliakov, L.G. Wu, Actin and ATP provide mechanical force to collapse fusing vesicles at the plasma membrane, Nature Communications, 7:12604, 2016. [article link] 

F. Caschera*, J.W. Lee*, K.K.Y. Ho, A.P. Liu, M.C. Jewett, Cell-free compartmentalized protein synthesis inside double emulsion templated liposomes with in vitro synthesized and assembled ribosomes, ChemComm, 52, 5467-5469, 2016*equal contribution, M.C. Jewett and A.P. Liu are co-corresponding authors [article link] 

A. P. Liu, Biophysical tools for cellular and subcellular mechanical actuation of cell signaling, Biophysical Journal, 111, 1-7, 2016. [article link]

2015

X. Tan, J. Heureaux, A.P. Liu, Cell spreading area regulates clathrin-coated pit dynamics on micropatterned substrate, Integrative Biology7, 1033 - 1043, 2015. [article link]

L.M. Lee, A.P. Liu, The application of micropipette aspiration in molecular mechanics of single cells, ASME Journal of Nanotechnology in Engineering and Medicine, 5(4): 040801-04081-6, 2015. (Themed issue on nanotechnology for biology and biomedical applications) [article link]

K.K.Y. Ho*, V.L. Murray*, A.P. Liu, Engineering artificial cells by combining HeLa-based cell free expression and ultrathin double emulsion template, Methods in Cell Biology, volume 128, Chapter 16, 303-318, 2015. *equal contribution [article link]

L.M. Lee, A.P. Liu, A microfluidic pipette array for mechanophenotyping of cancer cells and mechanical gating of mechanosensitive channels, Lab on a Chipvol 15, 264-273, 2015. [article link]

2014

J. Heureaux, D. Chen, V.L. Murray, C.X. Deng, A.P. Liu, Activation of a bacterial mechanosensitive channel in mammalian cells by cytoskeletal stress, Cellular and Molecular Bioengineering, vol 7 (3), 307-319, 2014. *Young Innovators Special Issue [article link] [journal cover] [featured article]   

E.M. Steel*, V.L. Murray*, A.P. Liu, Multiplex detection of homo- and heterodimerization of G protein-coupled receptors by proximity biotinylation, PLoS One, vol 9 (4), e93646, 2014. *equal contribution [article link]

C. Coyne, K. Patel, J. Heureaux, J. Stachowiak, D.A. Fletcher, A.P. Liu, Lipid bilayer vesicle generation using microfluidic jetting. J. Vis. Exp. (84), e51510, doi:10.3791/51510. [article link]

2013

Y. Shao*, X. Tan*, R. Novitski, M. Muqaddam, P.T. List, L. Williamson, J. Fu, A.P. Liu, Uniaxial cell stretching device for high resolution live cell imaging of mechano-sensitive functions, Review of Scientific Instruments, vol 84 114304, 2013. *equal contribution, J. Fu and A.P. Liu are co-corresponding authors [article link]

H. Lin, A.P. Liu, T.H. Smith, J. Trejo, “Dimerization and cofactoring between proteinase-activated receptors: implications for ligand and signaling specificity”, Pharmacological Reviews, vol 65 (4), 1198-213, 2013. [article link]

2011

D. Nunez, C. Antonescu, M. Mettlen, A,P. Liu, S.L. Schmid, D. Loerke, G. Danuser, “Hotspots organize clathrin-mediated endocytosis by efficient recruitment and retention of nucleating resources”, Traffic, vol 12 (12), 1868-78, 2011. [article link]

2010 

A.P. Liu, F. Aguet, G. Danuser, S.L. Schmid, “Local clustering of transferrin receptors promotes clathrin-coated pit initiation”, Journal of Cell Biology, vol 191 (7), 1381-1393, 2010. [article link]

D. Banerjee, A.P. Liu, N. Voss, S.L. Schmid, M.G. Finn, “Multivalent display of transferrin on virus-like particles by click chemistry and receptor-mediated endocytosis”, ChemBioChem, vol 11, 1273-1279, 2010.
[article link]

2009

A.P. Liu, D. Loerke, S.L. Schmid, G. Danuser, “Global and local regulation of clathrin coated pit dynamics detected on patterned substrates”, Biophysical Journal, vol 97 (4), 1038-1047, 2009.  [article link]

A.P. Liu, D.A. Fletcher, “Biology under construction: in vitro reconstitution of cellular processes”, Nature Reviews Molecular Cell Biology, vol 10 (9), 644-650, 2009. [article link]

2008 

A.P. Liu*, D.L. Richmond*, L. Maibaum, S. Pronk, P.L. Geissler, D.A. Fletcher, “Membrane-induced bundling of actin filaments”, Nature Physics, vol 4, 789-793, 2008.  *equal contribution [article link]

J. Stachowiak, D.L. Richmond, T.H. Li, A.P. Liu, S.H. Parekh, D.A. Fletcher, “Giant unilamellar vesicle formation and encapsulation by microfluidic jetting”, Proceeding of National Academy of Sciences, vol 105, 4697-4702, 2008. [article link]

2007

J.L. Choy, S.H. Parekh, O. Chaudhuri, A.P. Liu, C. Bustamante, M.J. Footer, J.A. Theriot, D.A. Fletcher, “Differential force microscope for long-timescale biophysical measurements” Review of Scientific Instruments, vol 78, 043711, 2007. [article link]

2006

A.P. Liu, D.A. Fletcher, “Actin polymerization serves as a membrane domain switch in model lipid bilayer”, Biophysical Journal, vol. 91, 4064-4070, 2006. [article link]

   See also New and Notable: M. Edidin, “Switching sides: The actin/membrane lipid  connection” Biophysical  Journal, vol. 91, 3963, 2006. [article link]

2005

A.P. Liu, D.A. Fletcher, “Photopatterning of actin filament structures”, Nano Letters, vol. 5, no. 4, 625-628, 2005.  [article link]

2001

D.H.C. Chen, A.P.C. Liu, Y. Koga, Excess Partial Molar Enthalpy of 1-Propanol in 1-Propanol-Acetone (or Tetramethyl Urea) - H2O at 25oC. Fluid Phase Equil., 189: 31-38, 2001.